At present, there are two reasons for the recurrence of candidal vaginitis. One is frequent reinfection, and the other is that the pathogen has not been completely removed after the last attack. The reason for frequent reinfection is mainly due to personal behavior and lifestyle:
1. Frequent sexual life, more sexual partners, and increased probability of sexual transmission.
2. Frequent vaginal irrigation causes abnormal changes in the vaginal environment, such as the imbalance of flora and the increase of acidity, which can lay the foundation for Candida reinfection.
3. Some patients "prevent" possible infection. Irregular use of broad-spectrum antibiotics also destroys the local defense mechanism of the vagina, resulting in frequent infection of flora imbalance.
4. Sharing bath towels with others
dildo shop , wearing underwear and wearing tights for a long time are also one of the elements of relapse.
one. Internal therapy
(1) nimycin: this product can inhibit Candida albicans, but it is not easy to absorb from the stomach and intestines, so it is only suitable for Candida albicans infection or atomization absorption in the treatment of respiratory infection. The underwear is used 3 times a day for 500000 ~ 1 million units a day for 1 to 2 weeks.
(2) Amphotericin B and ball erythromycin are effective in the treatment of visceral candidiasis, but they are toxic, so we should pay attention to observe that domestic Lushanmycin has similar curative effect with amphotericin B.
(3) clotrimazole: the adult daily dose of 2-3g was taken orally for three times for 2 weeks.
(4) ketoconazole: adult 200mg, once a day. Some people put forward this product 200mg, clothing every other day, the effect is the same.
(5) garlic injection 20~40ml, add glucose solution to intravenous drip, once a day. The curative effect is satisfactory and the toxicity is small.
(6) transfer factor intramuscular injection or internal administration of cimetidine 300 mg every other day, four times a day, can improve the cellular immune function of the body and help to promote the recovery of patients.
II. External use therapy
Skin and mucous membrane Candida albicans as long as the use of external therapy can be effective. Gentian violet
dog dildo , nystatin and amphotericin can be selected for clinical application.
B
Erythromycin and imidazole are used as the main drugs, which are prepared into solutions, ointments, paste or emulsions for use.
III. Local therapy
(1) 2%
Clotrimazole, miconazole or ketoconazole cream; or compound Raisuoxin liniment, external application, daily
2 times
clitoral vibrator , mainly suitable for many kinds of skin candidiasis. Papular candidiasis with red prickly heat can also be applied with sulfur calamine lotion containing mycin 4-6 times a day. Rash often needs to be powdered.
(2) nystatin smear (fungal disorder 100000, glycerol 10ml, distilled water 60ml) is mainly suitable for thrush and genital candidiasis, 2 or 3 times a day.
(3) Fibromycin suppository (51.1 million U) is suitable for candidal vaginitis, once a night for 1 week or 2 weeks.
(4) 50000 u of polyaldehyde to make mycin was added to saline 5ml, or amphotericin B5mg was added to water for injection.
20m
1. Inhaling aerosol 2 or 4 times a day is suitable for oral and respiratory Candida infection.
IV. Systemic therapy
Systemic therapy is mainly suitable for all kinds of visceral candidiasis and severe skin and mucosal Candida infection.
The main results are as follows: (1) nystatin: 2 million ~ 4 million u / day, orally for 4 times, 50 ~ 100 000 u / kgd for children. The drug is rarely absorbed in the intestine and is mainly used for gastrointestinal candidiasis.
(2) ketoconazole:
0.2g
Once a day. The course of treatment depends on the type of infection and the reaction of the patient. Patients with abnormal liver function should be used with caution.
(3) itraconazole: 200mg, once a day for more than 4 weeks.
(4) Amphotericin B (0.5~1mg/ kg ·d) intravenous drip, or combined with oral 5-fluorouracil (200mg/ kg ·d), may have a certain synergistic effect to improve the curative effect.
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